Diabetes genetics, biomarkers and epidemiology

Diabetes mellitus (DM) is a metabolic disorder marked by hyperglycemia. It is caused by either faulty insulin secretion or a malfunctioning biological function, or both. Type 2 diabetes is a progressive disease in which the body becomes resistant to the normal effects of insulin and/or gradually loses the ability of the pancreas to produce enough insulin. Pre-diabetes is defined as having blood sugar levels that are higher than normal but not yet high enough to be classified as type 2 diabetes. Gestational diabetes occurs when a woman who does not have diabetes develops high blood sugar levels during pregnancy.

Epidemiology

Genetics of type 1 diabetes

Genetics of type 2 diabetes

Monogenic forms of diabetes

Environmental factors (viruses, nutrients, toxins)

Diabetes epigenetics

Prediction and prevention of type 1 diabetes

Prediction and prevention of type 2 diabetes

Risk of diabetes in immigrant populations

Retinopathy

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